MolabIS: A Labs Backbone for Storing, Managing and Evaluating Molecular Genetics Data

Using paper lab books and spreadsheets to store and manage growing datasets in a file system is inefficient, time consuming and error-prone. Therefore, the overall purpose of this study is to develop an integrated information system for small laboratories conducting Sanger sequencing and microsatellite genotyping projects. To address this, the thesis has investigated the following three issues. First, we proposed a uniform solution using the workflow approach to efficiently collect and store data items in different labs. The outcome is the design of the formalized data framework which is the basic to create a general data model for biodiversity studies. Second, we designed and implemented a web-based information system (MolabIS) allowing lab people to store all original data at each step of their workflow. MolabIS provides essential tools to import, store, organize, search, modify, report and export relevant data. Finally, we conducted a case study to evaluate the performance of MolabIS with typical operations in a production mode. Consequently, we can propose the use of virtual appliance as an efficient solution for the deployment of complex open-source information systems like MolabIS. The major result of this study, along with the publications, is the MolabIS software which is freely released under GPL license at http://www.molabis.org. With its general data model, easy installation process and additional tools for data migration, MolabIS can be used in a wide range of molecular genetics labs

ĐẶC ĐIỂM DÒNG CHẢY VEN BỜ BẮC TRUNG BỘ (HÀ TĨNH - THỪA THIÊN-HUẾ) THỜI KỲ 4/2016

This paper presents the modeled results of general current pattern (daily average value) in Northern Central Vietnam Coast (Ha Tinh - Thua Thien-Hue) during April 2016. Study results show that in general, current flowed from the North to the South with small and instable velocity (V ≈ 0.1 - 0.2 m/s). From 2nd to 6th April current flowed from the South to the North. From 7th to 29th April current flowed from the North to the South. During 13rd to 16th April current velocity was weak (V ≤ 0.1 m/s). In the southern region of Thua Thien-Hue province, the direction of current was instable (from 6th to 9th and from 20th to 22nd April current flowed from the South to the North). Current distribution pattern from modeled results was in accordance with the propagation characteristics of surface water temperatures in the studied area through data analysis of satellite images.Bài báo trình bày kết quả tính toán trường dòng chảy tổng hợp trung bình ngày cho khu vực ven bờ Bắc Trung Bộ (Hà Tĩnh - Thừa Thiên-Huế) thời kỳ 4/2016. Kết quả nghiên cứu cho thấy trong thời gian nghiên cứu nhìn chung dòng chảy tổng hợp trung bình ngày có hướng từ bắc xuống nam, tốc độ tương đối nhỏ V ≈ 0,1 - 0,2 m/s và không ổn định. Từ 2-6/4/2016 dòng chảy tổng hợp trung bình ngày ven bờ có hướng từ nam lên bắc. Từ 7-29/4/2016 dòng chảy ven bờ có hướng từ bắc xuống nam. Các ngày 13-16/4/2016 dòng chảy tổng hợp trung bình ngày có tốc độ nhỏ (V ≤ 0,1 m/s). Khu vực phía nam Thừa Thiên-Huế dòng chảy tổng hợp trung bình ngày có hướng bị biến động mạnh nhất (các ngày 6-9/4 và 20-22/4 hướng dòng từ nam lên bắc). Đặc điểm phân bố dòng chảy tính toán tương đối phù hợp với đặc điểm lan truyền nhiệt độ nước tầng mặt tại khu vực nghiên cứu qua số liệu phân tích ảnh vệ tinh

Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions

General approach for parameterization of the inverse dynamic equation for industrial robot and 5-axis CNC machine

In practice, using the 5-axis CNC machines and industrial welding robots for fabricating more and more complex mechanical parts is an increasing demand. In this context, the tooltip of the machines/robots is usually required to move along a complex toolpath represented by a parametric equation such as Bezier, Spline or NURBS. Hence, computation of the inverse kinematics and dynamics e.g. velocities, accelerations, jerks and applied torques/forces in the joint space of a machine/robot when the tooltip tracks such as high curvature parametric curve is challenging. Therefore, this paper presents a general approach for the parameterization of the kinematic and dynamic equations of the machine/robot. By using the proposed method, the kinematics and dynamics model of a machine/robot can be formulated in the parametric domain, which is advantageous and applicable for the dynamic analysis of the 5-axis CNC machine/robot and other purposes

Effect of calophyllolide on myeloperoxidase (MPO) activity.

<p>All mice were sacrificed on day 1 and day 5 post-operation, and skin tissue samples were collected to assess MPO activity (n = 3 mice per group per experiment). Data are represented as mean ± SEM and compared by one-way ANOVA. *** P<0.001.</p

Three-Photon Absorption Induced Photoluminescence in Organo-Lead Mixed Halide Perovskites

International audienc

Effect of calophyllolide on HaCaT and RAW264.7 cell viability.

<p>HPLC chromatograms of the isolated calophyollide <b>(A)</b> and standard control <b>(B)</b>. This compound was recorded at 233 nm, and its retention time is 36.6 min. <b>(C)</b> No effect of CP on the viability of both HaCaT and murine macrophage RAW264.7 cells after 24 h treatment.</p